【摘 要】
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DNA recombination is a fundamental process of life.Archaea,as the third domain of life,share similarity in DNA recombination proteins and mechanism with eukaryo
【机 构】
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StateKeyLaboratoryofMicrobialTechnology,ShandongUniversity,27ShandaNanRd.,Jinan,250100
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DNA recombination is a fundamental process of life.Archaea,as the third domain of life,share similarity in DNA recombination proteins and mechanism with eukaryotic counterpart.In the last ten years or so,we have conducted systematic biochemical,genetic and structural study on the DNA recombination and repair mechanism using the model hyperthermophilic arhcaeon Sulfolobus.Hjc is a Holliday junction (HJ) cleavage endonuclease (HJ resolvase).
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