【摘 要】
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Objectives β-amyloid peptides(Aβ) induced oxidative damage contributes to the pathogenesis of neurodegenerative diseases and cerebrovascular system is vulnerable to oxidative stress.Our earlier study
【机 构】
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School of Public Health,Capital Medical University
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Objectives β-amyloid peptides(Aβ) induced oxidative damage contributes to the pathogenesis of neurodegenerative diseases and cerebrovascular system is vulnerable to oxidative stress.Our earlier study showed a clue that Genistein(Gen) might activate Nf-E2 related factor 2(Nrf2) signaling pathway to protect cerebrovascular cells from oxidative damage induced by Aβ,but the specific mechanismsand regulation targets are unclear.
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