The HO-1/EBP interaction alleviates the cholesterol-induced hypoxic status by activating PI3K/AKT an

来源 :天津高血压论坛2016暨天津市医师协会高血压专业委员会第一届年会 | 被引量 : 0次 | 上传用户:linnber
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  Objective :To investigate the Heme oxygenae-1 (HO-1)-mediated protective mechanism in cholesterol induced oxidative stress.Method :The HO-1 interaction proteins were screened using a profound co-immunoprecipitation (co-IP) coupled with proteomics, and profiled the global HO-1 interactome network using Gene Oncology (GO), Ingenuity Pathway Analysis (IPA) and cytoscape 3.3 analysis.The HO-1 and EBP interaction was confirmed by confocal microscope.
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