Especially in the field of proteomics research, fast and efficient miniaturized separation methods are required to analyze very small amounts of sample.As a result, there is a strong interest in the development of new high-efficiency support structures in capillary column format, such as fused-core capillary columns and monolithic materials [1].To assess the separation performance of columns with different morphologies the classical van Deemter curve does not longer suffice, since it does not incorporate the effect of column permeability on kinetic performance, which is one of the key drivers for the development of new (monolithic) support systems [2].As an alternative for the van Deemter curve, the kinetic plot can be used to compare the time required to obtain a specific number of plates [3].