【摘 要】
：
Bladder cancer is one of the most common cancers worldwide with transitional cell carcinoma (TCC) being the predominant form.Here we report an integrated analysis of TCC by both whole-genome and whole
【出 处】
：
2013年广东省医学会泌尿外科学学术年会
论文部分内容阅读
Bladder cancer is one of the most common cancers worldwide with transitional cell carcinoma (TCC) being the predominant form.Here we report an integrated analysis of TCC by both whole-genome and whole-exome sequencing of 99 individuals with TCC.Beyond confirming recurrent mutations in genes previously identified as mutated in TCC,we identified additional altered genes and pathways that are implicated in TCC.
其他文献
目的 研究在门诊洁净手术室实行美容手术的有效的消毒隔离措施.方法 我院自2010年9月投入门诊洁净手术室以来，采用合力的布局，从制度、人员、物品、卫生学监测等方面实施管理，落实具体措施，通过各种监测查出不足，进行分析及时整改，确保了各种美容手术的成功.结果 制订相应的门诊洁净手术室控制感染质量标准，使各项检测指标正常.578例美容手术无一例感染，术后恢复良好，成功率100％.结论 只有加深对洁净手
手术室护士工作在手术室内这一特殊环境中由于手术病人高度集中，加上各种创伤治疗技术，消毒剂的应用形成了手术室内特有的生物性、物理性、化学性环境，同时由于护理工作的高强度性使护理人员经常处于心理学和工效学的高度应激状态，这些不良的职业卫生因素对护理人员造成了慢性、长期性的职业影响。因此，重视并预防手术室护士职业的潜在危害，已引起多方关注。为提高护士的身心健康、对手术室各种潜在危害因素进行分析，并在现有
随着我国人民生活水平的提高，巨大儿及剖宫产率逐年上升，相应的剖宫产术中大出血的几率也有所上升。多为产妇凝血功能异常，剖宫产手术过程中胎盘因素(胎盘植入，胎盘粘连等因素)，子宫收缩乏力(双胎，子宫肌瘤等因素)，而引起剖宫产术中大出血。对我院14例剖宫产术中大出血病人的抢救配合进行回顾性的分析，体会到术中及时准确地判断大出血和迅速有效的抢救措施是降低产妇死亡率的关键。
总结了38例白化病眼球震颤手术的护理配合。术前与Hertel教授沟通手术方式,设计手术护理方案及应急预案,针对白化病患儿的特殊性,术前重点进行心理护理。通过充分的术前准备,恰当的手术配合,所有患儿均手术顺利成功。白化病是一种由于黑色素合成基因突变导致的眼、皮肤、毛发黑色素缺乏性遗传病,表现在眼部时患者虹膜、视网膜颜色浅淡或缺如,临床出现眼底着色不足、虹膜半透明、眼球震颤、高度屈光不正、视力下降等。
目的:研究在前列腺不同区带发生组织学前列腺炎的差异性及意义.方法:应用经直肠超声前列腺穿刺收集59例患者外周带组织(外周组),通过经尿道前列腺剜除术获得61例前列腺增生患者中央带及移行带组织(中央组),常规病理检查分析两组间组织学前列腺炎的发生情况.同时分析前列腺增生和前列腺癌中发生组织学前列腺炎的差异性.结果:外周组炎症检出率为:42％(25/59);中央组检出率为25％(15/61),两组之间
Purpose:Cyclooxygenase-1 (COX-1),which generally participates in normal physiological function,was found to be over expressed in ovarian cancer and related with tumor growth.The aim of this study was
Background:Myc regulates cell proliferation,differentiation and apoptosis in several cancers.N-myc downstream-regulated gene 2 (NDRG2),was reduced in renal cell carcinoma (RCC) tissues compared to adj
The documents about schistosomiasis of prostate are rare and most of them are case reports of concomitant prostatic schistosomiasis and adenocarcinoma.Here we report a case of schistosomiasis japonica
Purpose:The aims of this study were to evaluate the clinical significance and potential prognostic value of pregnancy up-regulated non-ubiquitous calmodulin kinase (PNCK) in clear cell renal cell carc
Purpose:To study the effect of Cx43 (Connexin 43)and GJIC(Gap Junctional Intercellular Communication) by the MSC treatment in the prostate cancer DU145 cell.Methods:Cx43 mRNA and protein were examined