四种物质对HaCat细胞氧化应激相关基因表达的影响研究

来源 :2015毒性测试替代方法与转化毒理学(国际)学术研讨会 | 被引量 : 0次 | 上传用户：ty_142857

【摘要】

：

目的研究过氧化氢、姜黄素、槲皮素及叔丁基对苯二酚四种物质对人表皮细胞84个氧化应激相关基因表达的影响.方法采用不同浓度的四种物质过氧化氢(0.5mM,1.25mM),姜黄素(5μM,20μM),槲皮素(200μM,500μM)及叔丁基对苯二酚(10μM,50μM)分别染毒HaCat细胞4h及24h后,采用RT-pcr方法检测HaCat细胞84个氧化应激相关基因的表达水平.

【作者】

：

褚洪迁 Penny Jones Paul Carmichael 魏雪涛郝卫东

【机构】

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北京大学公共卫生学院毒理学系食品安全毒理学研究与评价北京重点实验室,北京100191中国英国联合

【出处】

：

2015毒性测试替代方法与转化毒理学(国际)学术研讨会

【发表日期】

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2015年5期

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四种物质对HaCat细胞氧化应激相关基因表达的影响研究

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