【摘 要】
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Objective This study aim is to investigate using of bone marrow mesenchymal stem cells (BMSC) genetically engineered to produce interferon-b (IFN-b) as a gene delivery system to treat hepatocellular c
【机 构】
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Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University
【出 处】
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中华医学会第十六次全国病毒性肝炎及肝病学术会议
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Objective This study aim is to investigate using of bone marrow mesenchymal stem cells (BMSC) genetically engineered to produce interferon-b (IFN-b) as a gene delivery system to treat hepatocellular carcinoma (HCC) in vitro and in vivo.Methods To measure the effects on tumour cell growth in vitro, IFN-b-producing BMSC (BMSC/IFN-b) were co-cultured with the HCC cell line HepG2 and Huh7.ELISA was used to detect the IFN-b secretion in the BMSC culture condition medium (CM)
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