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Purpose: Toevaluatetheimagequalityandradiationdoseofhigh-pitchdual-sourceCTaortaangiographyusingautomated tubepotentialselectionincomparewithautomatedtubecurrentmodulationonathirdgenerationdual-sourceCTscannerwith electrocardiogramsynchronization. Material andmethods:59patientsunderwentwholeaortaangiographyona3rdgenerationdual-sourceCTdeviceoperatedin dual-sourcehigh-pitchECG-gatingmodewithapitchof3.0,collimationof2×192×0.5mm,andarotationtimeof0.25s. Interactivereconstructionalgorithmwereused.31patientswereenrolledingroup1,whounderwenttheexaminationwith automatedtubepotentialselection(carekV)usingavascularsettingwithapreferredimagequalityof288mAs/100kV.The volumeandflowofcontrastmediumandchasingsalinewereadaptedtothetubevoltage:100kV:45mlcontrast,4.5mL/s,50ml saline,5mL/s;90kV:40mlcontrast,4.0mL/s,45mlsaline,4.5mL/s;80kV:35mlcontrast,3.5mL/s,40mlsaline,4.0mL/s;70kV:30ml contrast,3.0mL/s,35mlsaline,3.5mL/s.28patientswereenrolledingroup2,whounderwenttheexaminationwithatubevoltage of100kV,andautomatedtubecurrentmodulation(caredose4D)usingareferencetubecurrentof288mAs.Acontrastmaterial bolusof45mLwithaflowof4.5mL/sfollowedbya50mLsalinechaserin5mL/swasused.Effectiveradiationdose,SNR,CNR andsubjectivediagnosticqualityofbothgroupswereevaluated. Results:Themeaneffectiveradiationdosewere2.48±0.80mSvingroup1and3.15±0.86ingroup2.Group1receivedalower effectiveradiationdoseincomparewithgroup2(p=0.003).TwogroupsshowednosignificantdifferenceinSNRorCNR(P>0.05). Subjectivediagnosticqualitywassimilarforbothgroups(P>0.05).Thecontrastmediumdosewasloweringroup1. Conclusion:ApplicationofautomatedtubepotentialselectiontechniqueinwholeaortaCTangiographyallowsradiationdose andcontrastmediumreductionwithoutaffectingimagequalityincomparewithautomatedtubecurrentmodulation.