Missense mutations in human Krüppel-like factor 11 (KLF11) lead to the development of diabetes.However, the role of KLF11 in peripheral tissues is largely unknown.
RAS proteins are small GTPases that act as molecular switches,transducing signals from many activated receptors that regulate cell proliferation,survival,and differentiation.
Recently, a novel class of transcripts, long noncoding RNAs (lncRNAs),is being identified at a rapid pace.These RNAs act critical roles in diverse biological processes including tumorigenesis.
Angiogenin is a 14kDa protein that is significantly upregulated in many types of human cancers.It stimulates both tumor angiogenesis and cancer cell proliferation by promoting ribosomal RNA (rRNA) tra