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用９９ｍＴｃ┐亚甲基二膦酸盐（９９ｍＴｃ┐ＭＤＰ）对肺癌病人进行全身骨显像，探讨肺癌骨转移的特点和规律。方法我院１９９５～１９９７年１２４例肺癌骨转移病例，对骨转移的部位、病理类型、分期进行回顾性综合分析。结果肺癌骨转移发生率为２２．２％；骨转移部位以胸部骨骼为最多，其它依次为脊柱、骨盆，肺腺癌较其它病理类型肺癌容易发生骨转移；淋巴结侵犯越广泛，则骨转移的机会也越多；全身骨显像诊断肺癌骨转移阳性率要明显高于Ｘ线摄片与ＣＴ检查阳性率。结论肺癌患者应常规行全身骨显像。
99mTc┐methylenediphosphonate (99mTc┐MDP) was used to perform whole-body bone imaging on lung cancer patients to investigate the characteristics and regularity of bone metastasis of lung cancer. Methods A total of 124 cases of bone metastases from lung cancer from 1995 to 1997 in our hospital were retrospectively analyzed on the locations, pathological types, and stages of bone metastases. Results The incidence of bone metastasis in lung cancer was 22.2%. The bone metastases were the most common in the thoracic skeleton. Others were in the order of spine and pelvis. Lung adenocarcinoma was more prone to bone metastases than other pathological types of lung cancer. The more extensive lymph node invasion, the more bone metastases were. The more chances, the higher the positive rate of bone metastases in the diagnosis of lung cancer with bone metastases is higher than that of X-ray and CT. Conclusions Patients with lung cancer should routinely perform whole body bone imaging.