Background:Surgical donor-site morbidity, financial resources and rehabilitation time are the main economic concerns in the field of modern Reconstructive Microsurgery.The crux of the economic tissue transfer is how to manage the resources that are given.The "KISS" flap design was developed to maximize the size of the harvested flap while minimizing the donor site morbidity.Methods:The main concept of the "KISS" technique is to harvest multiple skin paddles (smaller than those raised with the traditional techniques) nourished by independent perforators or branches from the same or from the multiple vascular source and stacked side-by-side at recipient site to exactly match the defect and close the donor site directly.The "KISS"concept can be widely applied in both microsurgical free flap surgery and pedicle flaps for reconstruction, including ALT, PIAPF, PAPF, IMAPF and LD flap which are the most popular used flaps.The "KISS" technique allows for the reconstruction of a large defect with a large flap while maintaining primary closure of donor defect without skin graft.Results:According to the blood supply of the main pedicle, the "KISS" flaps are classified into 2 style groups.Style A group includes flaps with a single vascular source.This group consistsof 3 types of flaps: Perforator/branch based kiss flaps (Type Ⅰ);Myo-based(muscle-based) kiss flaps (Type Ⅱ); Flow-through kiss flaps (Type Ⅲ).Type Ⅰ can be also subdivided into 3 subtypes: Perforator-perforatorbased; Perforator-branch based and Sub-perforator based.Style B group consists of 2 types of flaps with multiple vascular sources: Cutaneous based kiss flap (Type Ⅰ); perforator based kiss flap (Type Ⅱ).All the different types of "KISS" flaps have their own unique techniques in both flap design and harvesting.Conclusion:Faced with the challenge of lack of suitable donor sites, the decrease of financial resources and the need of saving rehabilitation time, we aim to discuss the most economical and efficient methods used to reconstruct defects of different sizes and involving different body areas.The keystone of "KISS" flap is to convert the flap width to flap length.This particular flap design avoids the need for a second donor site from which a skin graft should be taken, thus resulting in better cosmesis and functional outcome for donor sites.By minimizing the donor site morbidity, these applications can be widespread and the potential advantages increased.