【摘 要】
：
Objective:To get the message of the abnormal pregnant risk when one of parent was the mosaics karyotype.Case report:The couple was referred for antenatal examination.The karyotype of husband was 45,XX
【机 构】
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Prenatal diagnosis center,Departments of Obstetrics and Gynecology,Southwest Hospital,Third Military
【出 处】
：
中华医学会2012年医学遗传学年会暨全国第十一次医学遗传学学术会议
论文部分内容阅读
Objective:To get the message of the abnormal pregnant risk when one of parent was the mosaics karyotype.Case report:The couple was referred for antenatal examination.The karyotype of husband was 45,XX,der(16)t(16;22)(q24;q11.2),-22[59]/45,XX,der(1)t(1;22)(p36;q11.2),-22[11]/45,XX,der(22)t(22;22)(p13;q11.2),-22[10].His first daughter was 45,XX,der(16)t(16;22)(q24;q11.2),-22 [45]/45,XX,der(9)t(9;22)(q34;q11.2),-22[30]/45,XX,der(5)t(5;22)(q35;q11.2),-22[25].The couple was checked to the amino fluid and the fetal karyotype was 46,XY.The chromosome of daughter proceeded to recombination after she inherited her fathers abnormal chromosome.Conclusion:So the parent with abnormal mosaics karyotype should be progressed careful prenatal diagnosis to get a normal child.
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