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5. Caspase-1 knockout confers resilience to chronic stress via regulating the surface stability of AMPA

Caspase-1 knockout confers resilience to chronic stress via regulating the surface stability of AMPA

来源 :第三届国际神经疾病大会暨2016脑网络与脑疾病高峰论坛 | 被引量 : 0次 | 上传用户：fly_wing

【摘 要】

：

Inflammatory processes have been implicated in the pathophysiology of mood‐related disorders; however,whether caspase‐1,a classic inflammatory caspase,contributes to depression remains largely unknown

【作 者】

：

Ming-Xing Li Hui-Ling Zheng Zhuang-Li Hu Peng-Fei Wu Li-Hong Long Fang Wang Jian-Guo Chen 

【机 构】

：

Department of Pharmacology,School of Basic Medicine,Tongji Medical College,Huazhong University of Sc

【出 处】

：

第三届国际神经疾病大会暨2016脑网络与脑疾病高峰论坛

【发表日期】

：

2016年10期

【关键词】

：

Caspase-1 Depression-like behaviors AMPARs 

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　　Inflammatory processes have been implicated in the pathophysiology of mood‐related disorders; however,whether caspase‐1,a classic inflammatory caspase,contributes to depression remains largely unknown.We examined the role and underlying mechanisms of caspase‐1 in depression.

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