电针胃经穴大鼠体液的1H NMR代谢轮廓分析

来源 :第十八届全国波谱学学术年会 | 被引量 : 0次 | 上传用户:cj76680978
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胃粘膜损伤是由于情志应激、理化因素、微生物等因素引起的胃粘膜炎症、糜烂和出血的疾病.现代研究表明多种难治性胃病首先表现为胃粘膜损伤,进一步导致胃粘膜坏死、腺体萎缩、穿孔、癌变等恶劣后果.目前临床和实验研究皆证实针灸对胃粘膜损伤具有很好的修复作用[1,2],但修复机制和物质基础尚未清楚.本文采用基于NMR的代谢组学方法,研究电针胃经穴对大鼠血液尿样中的内源性代谢产物,分析比较对照组、模型组、电针胃经组和电针胆经组的代谢差异,寻找电针胃经对大鼠胃粘膜损伤修复作用的物质基础.
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