Custom Peptide Microarrays for Comprehensive Antibody and Serum Analysis

来源 :2011第三届中国北京抗体大会 | 被引量 : 0次 | 上传用户:zhaobaodong2006
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  In recent years, DNA chips have revolutionized genome research.A similar trend is predicted for peptide chips in proteome research.They can be applied for epitope mapping of monoclonal antibodies upon afTnity maturation, the analysis of antibody responses in sera upon infection or immunization, general protein interaction studies, the characterization of enzymes and enzyme substrates, or the design of new peptides as affinity tags, drug candidates or vaccines.Due to complex manufacturing processes, however, peptide chips available fall short of costs, spot density and thus information content of corresponding DNA-chips by far.
其他文献
据医学生理学家们研究,人类的吻与人类的肌肤饥饿是分不开的,所有的高等动物都有一种需要被抚摸的欲望.如果这种需求不能满足,就会发生一系列生理、病理、心理上的变化.
  Epitope mapping is often an important component ofmAb characterization.Linear (continuous) epitopes can be readily identified by probing solid-phase arrays
会议
  Anti-Endothelial Cell Antibodies (AECA) comprise a heterogeneous population of autoantibodies directed to various, so far poorly characterized endothelial s
会议
日本电报电话公司(NTT)在原有的F-400光纤系统的基础上设计出传输波长为1.5μm的新型通信系统,原系统传输波长为1.3μm,它是纵贯日本本土的远距离电话通信系统的主干线。该
随着我国“入世”进程的加快,外资银行将全面介入国内金融业务,这将对我国金融业的发展、金融监管和安全带来巨大的挑战。文章认为,对外资银行的引进是一个持续、渐进的过程,对外
澳大利亚电信公司研究所,研究了在澳大利亚任何地区都可使用现有澳大利亚卫星组织的卫星系统进行双向通信的手提式地球终端业务。该所的研究项目中,主要是直径小于1m的天线
  Multiple sclerosis (MS) is an autoimmune disease of CNS, resulting in demyelination, axon loss, and development of disability.Autoantibodies (autoAbs) in MS
会议
  High titers, specificity, ability to neutralize toxic compounds, affinity and avidity are intrinsic qualities required for antibodies antivenom of snakes.Th
会议
[摘 要] 本文简要的分析了企业物资采购成本的组成,阐述了对物资采购成本控制的相关认识,从影响物资采购成本的条件、物资采购流程控制进行了探讨和深究,从这些基本问题中整理出降低物资采购成本的几点应对措施。并提出了物资采购管理中降低成本,并且总结出了物资采购管理中降低成本,必须要树立物资采购全成本控制的新理念。  [关键词] 物资采购成本 采购流程控制 全成本控制的理念  物资采购成本是
  Background: Anti-SSa antibodies are useful in the diagnosis of autoimmune disease, particularly primary and secondary Sjogrens Syndrome.They are also found
会议