Aim To research the analgesic interaction between fospropofol and alfentanil.Methods The effects of fospropofol, alfentanil, and the combinations were examined in formalin-inducedpaw inflammatory hype
Aims a analytical method based on LC-MS/MS has been developed for the determination of brazilin in rat plasma, urine,feces and tissues.Methods Biological samples were processed with ethyl acetate cont
Aims To design, synthesis and evaluate novel classes of N-aryl-2-arylthioacetamides as non-nucleoside reverse transcriptase inhibitors (NNRTIs).Methods The compounds were performed by the reaction of
Aims A sensitive LC-MS/MS method was developed for the determination of zaltoprofen in human plasma and urine.Methods The biological samples were precipitated by acetonitrile containing 0.1％ formic ac
Aim AMP-activated protein kinase (AMPK) is a key energy sensor that regulates cellular energy homeostasis.We reviewed the current anti-cancer drugs of combined cancer therapy based on AMPK activity re
AIMS The present study was to determine whether diumal variations of cephalexin (CEP) pharmacokinetics exist in postprandial or fasting male volunteers.METHODS This is a study consisted of two randomi
AIMS To compare the effects of amlodipine (AML) on the bioavailability of cephalexin (LEX) and cefuroxime axetil (CXM).METHODS Twenty four healthy males were randomized into four treatments according
AIMS To investigate the effect of zinc sulfate on cephalexin (CEP) pharmacokinetics when administered concurrently or at strategically spaced dosing times designed to avoid the potential interaction i
目的 探索加强科室文化建设的有效途径,造就一支高素质的员工团队,塑造医院良好社会形象,拓宽医院生存发展空间,增强医院综合竞争力.方法 通过对科室文化内涵、组成与现状的分析,提出搞好科室文化建设,是提高医院竞争实力,推动医院可持续发展的必由之路,并从五个方面论述了如何建设科室文化.
Objective Carbamazepine (CBZ) is a commonly prescribed antiepileptic drug.Adverse effects and drug-drug interaction are the two major concerns for its clinic application.Methods CBZ is mainly metaboli