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  5. Both selenium deficiency and supplementation induced myocardial injuries in GPx-1P198L transgenic mi

Both selenium deficiency and supplementation induced myocardial injuries in GPx-1P198L transgenic mi

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：wumdk
【摘 要】
：
Background Both selenium (Se) deficiency and supplementation resulted in multiple detrimental effects in human and animals.The GPx-1 (Pro198Leu) polymorphism is associated with Se deficiency as well a
【作 者】
：
Wang Suqin Niu Xiaolin Gao Dengfeng Zhu Yanhe 
【机 构】
：
Department of Cardiology,Second Affiliated Hospital,Xi'an Jiaotong University,Xi'an,Shaanxi,China
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
【发表日期】
：
2014年3期
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Background Both selenium (Se) deficiency and supplementation resulted in multiple detrimental effects in human and animals.The GPx-1 (Pro198Leu) polymorphism is associated with Se deficiency as well as impaired GPx-1 activity.Studies reported that the Leu allel was less responsive to Se repletion than the Pro allel.Thus,the present study was carried out to observe the relationships between Se deficiency as well as supplement and overexpression of GPx-1-198Leu in myocardial inj uries.
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