Regenerative therapy has gained its own potential as a future therapeutic modality for the treatment of intractable diseases.Delivery of stem cells might be an essential part in the regenerative therapy.Current status of stem cell delivery is mostly limited to bone marrow-derived stem cells,umbilical cord blood stem cells and adipose derived stem cells remaining the needs to improve their regenerative potential and isolation efficiency.Tissue resident stem cells can raise the issues to overcome the current limitations.