Molecular probe for measuring proteostasis decline in cells

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：lovewxb1982

【摘要】

：

【作者】

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Yuning Hong

【机构】

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Department of Chemistry and Physics,La Trobe Institute for Molecular Science,La Trobe University,Mel

【出处】

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中国化学会第十届全国化学生物学学术会议

【发表日期】

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2017年10期

【关键词】

：

Proteostasis protein folding neurodegenerative disease fluorescence

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　　Maintaining proteostasis is an essential housekeeping function for cell survival.It involves chaperones and degradative pathways to ensure proteins fold correctly and to remove those that are misfolded,damaged or aggregated.When proteostasis becomes unbalanced,unfolded proteins can accumulate and aggregate.

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