【摘 要】
：
Purpose:Amniotic membrane (AM) is widely used as a carrier for limbal epithelial stem cell ex vivo expansion.However, the thick stroma of AM affects the postoperative corneal transparency.In this stud
【机 构】
：
Eye Institute of Xiamen University,Fujian Provincial Key Laboratory of Ophthalmology &Visual Sci
【出 处】
：
首届全国组织修复与再生医学大会暨国际组织修复与再生医学学术研讨会
论文部分内容阅读
Purpose:Amniotic membrane (AM) is widely used as a carrier for limbal epithelial stem cell ex vivo expansion.However, the thick stroma of AM affects the postoperative corneal transparency.In this study, we developed an ultrathin AM (UAM) and evaluated its biomaterial characteristics and efficacy in corneal epithelium tissue-engineering.
其他文献
Cancer and diabetes are two multifactorial chronic diseases with tremendous impact on health worldwide.A significantly enhanced risk for many forms of cancers has been identified in patients with diab
Background and Purpose Although the receptor-interacting protein l kinase (RIPIK)-regulated necroptosis can be evoked by cerebral ischemia, its effects and mechanisms in mediating neuronal and astrocy
Recent studies have identified critical roles for cytokine IL-17A in the development of chronic fibroproliferative diseases including hepatic fibrosis.However, the precise role and mechanism of IL-17A
Alzheimers disease (AD) is the most common form of dementia, the pathological hallmarks which are the accumulation of senile plaques and neurofibrillary tangles (NFTs) in the brain.Autophagy is the mo
We investigated the mechanisms underlying damage to rat small intestine in heat-induced stress.Eighteen Sprague-Dawley rats were randomly divided into a control group and a 3-day stressed group treate
Autophagy is a physiological process that is vital to homeostasis by clearing up damaged or aged organelles in cells. Autophagy also acts as a "double-edge sword" in tumor therapy. It enables tumor ce
代谢综合征为一种常见代谢性疾病,已构成全球性的健康问题.新近研究提示,Tribbles同源蛋白3 (TRB3)在调控糖尿病心肌病中发挥重要作用,提示TRB3可能介导机体代谢损伤.我们发现,高脂膳食诱导的小鼠代谢综合症导致肝脏、心脏、肾脏、肺脏中TRB3与自噬底物p62的水平增加,并且肝脏中TRB3与p62存在明显共定位.针对小鼠肝脏进行研究发现自噬上游信号通路活化,然而自噬底物p62以不可溶形态大
Silibinin, a biologically active compound isolated from the fruits and seeds of Silybum marianum L, has been reported to exhibit antioxidative, anticancer, cardial protective and neuro-protective effe
研究背景:多药耐药(multiple drug resistance,MDR)是肿瘤逃避治疗的机制之一,DEDD作为促凋亡因子,其可通过与PI3KC3/Beclin1复合物相互作用激活自噬,进而促进自噬相关Snail/Twist降解,抑制/逆转EMT进程. 目的:研究DEDD基因在MCF-7细胞肿瘤耐药中的作用,为乳腺癌的治疗提供新的策略和实验依据.方法:MTS法检测不同浓度及作用时间的阿霉素、紫
目的：讨Matrigel基底膜基质对人外泌汗腺细胞的分化作用.方法：取手外科手术患者自愿捐赠的正常手指全层皮肤,经Ⅱ型胶原酶消化分离出汗腺组织,贴壁培养,待原代细胞达80％融合后,收集细胞,部分细胞制成爬片行二维细胞免疫荧光检测CK7、CK14和α-SMA抗原表达.原代汗腺细胞(2×106)与1ml浓缩型Matrigel基底膜基质混匀后注射至裸鼠腹股沟皮下,共24只裸鼠,每个时间点3只裸鼠,于注射