【摘 要】
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Penehyclindine (PHCD), a new compound which functions well as anticholinergic, has been proposed to reduce lung and lethal toxicity.The mechanisms responsible for the effects of Penehyclindine hydroch
【机 构】
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Department of Anesthesiology, Affiliated Provincal Hospital, Anhui Medical University, Hefei 230001,
【出 处】
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中华医学会第22次全国麻醉学术年会
论文部分内容阅读
Penehyclindine (PHCD), a new compound which functions well as anticholinergic, has been proposed to reduce lung and lethal toxicity.The mechanisms responsible for the effects of Penehyclindine hydrochloride remain obscure.The purpose of the present study was to examine whether PHCD inhibits pulmonary apoptosis during acute lung injury induced by lipopolysaccharide (LPS) by regulate the apoptosis-regulating Bcl-2 familymembers (ie, Bcl-xL and Bax) expressions in the lung.
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