A clinical study on anti-HBV-DC-MTL in the HBeAg negative chronic hepatitis B virus infection

来源 :中华医学生物免疫学会第二届学术年会 | 被引量 : 0次 | 上传用户:shelllbw
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Aims:To observe the clinical efficacy of anti-HBV-DC-MTL,the dendritic cells(DC) and mixed T lymphocyte(MTL)originating from PBMC sensitized by HBsAg,in HBeAg negative chronic hepatitis B virus(HBV) infection.Methods:19 inactive HBsAg carriers and 19 chronic hepatitis B(CHB) patients were recruited in the study.PBMCs were obtained from 50ml peripheral blood.Anti-HBV-DC was proliferated from adherence PBMCs under the induction by GM-CSF and IL-4,and sensitized with 50μg HBsAg.
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