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  5. One-step and interference-free SERS signal amplification detection for circulating microRNAs in huma

One-step and interference-free SERS signal amplification detection for circulating microRNAs in huma

来源 :2016年分析化学前沿国际研讨会及中美分析化学研讨会 | 被引量 : 0次 | 上传用户：yellowfly1
【摘 要】
：
　　MicroRNAs(miRNAs)are class of small,endogenous,single-stranded noncoding RNAs of about 20-24 nucleotides long.Surface enhanced Raman scattering(SERS)has bee
【作 者】
：
Dandan Ma Jing zheng Ronghua Yang 
【机 构】
：
CollegeofChemistryandChemicalEngineering,StateKeyLaboratoryofChemo/BiosensingandChemometrics,HunanUn
【出 处】
：
2016年分析化学前沿国际研讨会及中美分析化学研讨会
【发表日期】
：
2016年6期
【关键词】
：
Circulating MicroRNAs SERS signal amplification 
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　　MicroRNAs(miRNAs)are class of small,endogenous,single-stranded noncoding RNAs of about 20-24 nucleotides long.Surface enhanced Raman scattering(SERS)has been used as a molecular and cellular analytical technology with extremely high sensitivity.In this study,we proposed a one-step and interference-free amplification sensing platform for circulating miRNAs detection in human serum.The detection limit of the proposed method can reach 5 fM,which could be used for the direct detection of circulating miRNAs in serum from patients.
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