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Background:It is well known that recurrent epileptic seizures will affect cognitive function in children,but it is unclear of intelligence quotient (IQ) profile of the non-epilepsy children with familial epilepsy.In the present study,we investigated the IQ profile of the children with familial generalized seizures.Materials and methods:28 children with familial Generalized Tonic-Clonic Seizures (GTCS) but no other neurological findings from 20 epilepsy families in the Southern Anhui Mountain Area of China were included in the epilepsy group.