Notch signaling pathway plays a key role in cell proliferation and development.They are also closely related to an inverted CCAAT box binding protein (ICBP9
Transforming growth factor-beta (TGF-β) suppresses T cell function to promote tumor immune escape.The essential roles of B7-H3 and B7-H4 have been uncovere
Background: TRIM31, an E3 ubiquitin ligase, is a member of the tripartite motif-containing protein (TRIM) family composed of a RING-finger, a B-box and a co
immunotherapy is the hot spot in the treatment of tumor.After undergoing active immunotherapy, passive immunotherapy and adoptive cellular immunotherapy, pe
Anisomycin, an antibiotic produced by Streptomyces, strongly induces apoptosis in different histological sorts of cancer cells in vitro, superior dramatical
Background: The pro-inflammatory cytokine interleukin-6 (IL-6) represents a keystone cytokine in infection, cancer and inflammation.Recent studies suggest t