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  5. Cocrystal and Salt Formation of Tranilast

Cocrystal and Salt Formation of Tranilast

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：zhangyanfangzhang
【摘 要】
：
The usage of many solid dosage form drugs is often limited by its bioavailability, which is often limited by their physicochemical properties, such as solubility, stability and so on.Salt formation is
【作 者】
：
Feng Chen Jia-Mei Chen Tong-Bu Lu 
【机 构】
：
School of Chemistry and Chemical Engineering,Sun Yat-Sen University,Guangzhou,China
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
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The usage of many solid dosage form drugs is often limited by its bioavailability, which is often limited by their physicochemical properties, such as solubility, stability and so on.Salt formation is the most common method for improving solubility and dissolution rates of acidic and basic drugs, while cocrystal formation plays an important role in the solubility improvement of neutral drugs.
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