Asymmetric Formal Synthesis of (-)-Swainsonine Using CSI-mediated Stereoselective Amination

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户：lsy999

【摘要】

：

【作者】

：

Yang Hye Ran Qing Ri Li Guang Ri Dong Yong Rae Hong In Su Kim Young Hoon Jung

【机构】

：

School of Pharmacy,Sungkyunkwan University,Suwon 440-746,Korea

【出处】

：

The 24th International Society of Heterocyclic Chemistry Con

【发表日期】

：

2013年4期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Polyhydroxylated indolizidine alkaloids are among the most interesting discoveries in the field of natural products.They are distributed widely in many plants and microorganisms, and have been reported to exhibit a range of biological activities including immunoregulatory activity, anti-HIV and anticancer activity.

其他文献

Reaction of Trithienylstibanes with Acyl Chlorides under Iron Trichloride Catalyst

Reaction of trithienylstibanes with various acyl chlorides in the presence of iron trichloride catalyst led to Friedel-Crafis type acylation at ipso-position to form acyl thiophenes in high yields.The

会议

Tandem Photo-Thermo-Photo Reaction of Dichlorocoumarin and 1,1-Diphenyl Ethylene

Highly fluorescent aromatic compounds have always been attracting organic and bioorganic chemists.They are widely used as labeling motifs in bio-imaging system.And these hetero aromatic compounds have

会议

Asymmetric Cascade Annulation via Enantioselective Oxa Diels-Alder Cycloaddition of in Situ Generate

An asymmetric cascade reaction of metallo-isochromenylium has been successfully established with multiple-bond formation viaan enantioselectiveoxa Diels-Alder reactionbycooperative catalysis of Pd(OAc

会议

Sinomenine Derivatives Embedded with Pyrazine Ring Exhibiting Potent TNF-α Inhibitory Activity

A number of sinomenine derivatives with embedment of pyrazine ring, a frequently applied drug fragment have been synthesized regioseleetively.A preliminary biological study of the regioisomeric mixtur

会议

One-step Synthesis of Indoloazocines via Gold-Catalyzed Reaction of Indole Functionality with Intern

A variety of indoloazocines can be readily prepared by 8-endo-dig cyclization of alkynylindole substrates and following rearrangement by catalysis of Ph3PAuNTf2 or other gold complexes.The reaction co

会议

Synthetic Studies on Erythrina Alkaloids

The first asymmetric total synthesis of erythraline, one of the representative members of erythrina alkaloids, has been achieved in 17 steps and 3.6％ overall yield starting from piperonal.

会议

Synthetic Studies on Ecteinascidin 743

The key intermediate ofecteinascidin 743[1] was efficiently synthesized from sesamol in 11 steps and 25％ overall yield.The key steps are a Noyori reduction, a diastereoselective Claisen rearrangement,

会议

Copper-Catalyzed Aerobic Transformations of Amidines toward Synthesis of Nitrogen-Containing Heteroc

In this presentation, we report two types of copper-catalyzed aerobic transformations of amidines, including: 1) [3+2]-annulation of N-alkenylamidines via concerted diamination of alkene tethers for t

会议

Rh(Ⅰ)-Catalyzed Trapping Ammonium Ylides by β-Nitroacrylates to Construct 3-Aminopyrrolidin-2-one De

3-Aminopyrrolidin-2-one derivatives are important ones of heterocyclic compounds with a wide array of bioactivities.Trapping ammonium ylides[1] in situ generated from diazo compound 1 and aromatic ami

会议

Syntheses of D-Fagomine and 6-Deoxyfagomine via a Highly Regioselective and Diastereoselective Allyl

Discovery of polyhydroxylated piperidines (azasugars) is one of the most notable achievements in the field of natural products.They bind specifically to the active sites of glycosidases by mimicking t

会议

Asymmetric Formal Synthesis of (-)-Swainsonine Using CSI-mediated Stereoselective Amination

与本文相关的学术论文