The effect and mechanism of Deferoxamine on Iron Accumulation-Induced bone loss in Ovariectomized C5

来源 :中华医学会第八次全国骨质疏松和骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户:gellycgy
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Iron has recently been recognized as an independent risk factor for postmenopausal osteoporosis,but the mechanisms leading to iron-related bone loss are not fully determined.Reportedly,Female menstrual discharge 36 mg iron a year,several years afierpostmenopausal can form the accumulation of iron.But the mice donthave the phenomenon of menstruation,after ovariectomy the level of iron in the body is not to rise.So this research adopts theovariectomized mice model of ferric ammonium citrate(FAC)intervention to simulate postmenopausal osteoporosis patientswith iron accumulation.
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