The orphan nuclear receptor Nur77 regulates AMPK activity through LKB1 subcellular localization in g

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户:dongchangnie
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AMP-activated protein kinase (AMPK) is an evolutionarily conserved metabolic sensor crucial for the cellular energy homoeostasis.In response to reduced energy supply,AMPK switches off Adenosine-5-triphosphate (ATP)-consuming pathways,including those for fatty acid synthesis and gluconenogenesis,and activates ATP-generating pathways,such as fatty acid oxidation and glycolysis.
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