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  5. The Clinical Significance of OPN in Blood for Non-Small Cell Lung Cancer Patients and Its Biological

The Clinical Significance of OPN in Blood for Non-Small Cell Lung Cancer Patients and Its Biological

来源 :首都医科大学第三届研究生学术论坛 | 被引量 : 0次 | 上传用户：hbffff
【摘 要】
：
Background: Osteopontin (OPN) is a secreted matrix glycoprotein.Alteration of OPN expression has previously been reported to play an important role in cancer aggressive behavior.The current study soug
【作 者】
：
Chengcheng Hao Guifang Du Yanan Gu Mu Hu Xiuyi Zhi Shan Cheng Wen G.Jiang 
【机 构】
：
Department of Biochemistry and Molecular Biology,Capital Medical University, Beijing 100069, China;C
【出 处】
：
首都医科大学第三届研究生学术论坛
【发表日期】
：
2015年9期
【关键词】
：
OPN NSCLC metastasis adhesion invasion 
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　　Background: Osteopontin (OPN) is a secreted matrix glycoprotein.Alteration of OPN expression has previously been reported to play an important role in cancer aggressive behavior.The current study sought to investigate the level of OPN expression in a cohort of patients with non-small cell lung cancer (NSCLC), the association with clinical implication and outcomes, and the molecular and cellular impact of the protein on lung cancer cells.
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