β肾上腺素受体激酶抑制剂对心力衰竭大鼠心功能的影响及其机制研究

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：guanhuaicn

【摘要】

：

目的:对心肌梗死后心力衰竭大鼠经外周静脉注射β肾上腺素受体激酶抑制剂(β-adrenergic receptor kinase inhibitor,β ARKct),研究其对心功能的影响.方法:使用体重250g左右雄性SD大鼠,通过结扎冠状动脉左前降支形成急性心肌梗死,4周后形成心力衰竭.将急性心肌梗死后心力衰竭大鼠随机分为对照组、实验组及假手术组,分别经尾静脉注射Ad-β ARKct或Ad空载体

【作者】

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陈晖

【机构】

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首都医科大学附属北京友谊医院

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

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β肾上腺素受体激酶抑制剂对心力衰竭大鼠心功能的影响及其机制研究

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