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Objective:Adipokine-inducedinflammationplaysrolesinthepathogenesisofhumanosteoarthritis(OA).Chemerinisanovel chemoattractantadipokinethatisassociatedwithmetabolicsyndromeandinflammation.Thepurposeofthisstudywasto investigatewhetherhumanplasmachemerinisassociatedwiththeseverityofkneeOA.