【摘 要】
：
目的:研究急性重症脑梗死患者外周血CD8+T淋巴细胞的毒性功能状态.方法:30名重症急性脑梗死患者起病后6小时收集静脉血,分离外周血单核细胞,采用流式细胞仪检测病毒多肽刺激后CD8+T淋巴细胞的细胞表面CD107a、细胞内IFN-γ、TNF-α的表达和细胞增生反应,与健康志愿者的检测结果对比.结果:同健康志愿者相比,病毒多肽刺激后脑梗死患者的CD8+T淋巴细胞CD107a表达、细胞内IFN-γ和T
【机 构】
：
同济大学附属东方医院神经内科 新疆维吾尔自治区喀什地区莎车县人民医院脑系科
【出 处】
：
中华医学会第十六次全国神经病学学术会议
论文部分内容阅读
目的:研究急性重症脑梗死患者外周血CD8+T淋巴细胞的毒性功能状态.方法:30名重症急性脑梗死患者起病后6小时收集静脉血,分离外周血单核细胞,采用流式细胞仪检测病毒多肽刺激后CD8+T淋巴细胞的细胞表面CD107a、细胞内IFN-γ、TNF-α的表达和细胞增生反应,与健康志愿者的检测结果对比.结果:同健康志愿者相比,病毒多肽刺激后脑梗死患者的CD8+T淋巴细胞CD107a表达、细胞内IFN-γ和TNF-α合成均显著降低(P＜0.01),但细胞增生反应无差异(P＞0.05);脑梗死组未经病毒多肽刺激的CD8+T淋巴细胞IFN-γ和TNF-α含量略低(P＜0.05).
其他文献
Object Periostin is an extracellular matrix secreted protein, and some studies have demonstrated that it enhances tumor genesis and metastasis.This study assesses the predictive and prognostic roles o
The effects of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor Apocynin on the enhanced hypoxia induced factor-1α (HIF-1α) and endothelin-1 (ET-1) expression, elevated systolic b
Objective The purpose of this study was to understand the pathological correspondence to the "reversed halo" sign (RHS) in adult pulmonary tuberculosis, and to summarize the clinical characteristics o
Objective To study the incidence of influenza (Flu) virus infection in hospitalized acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
Objective To promote the understanding of smoking related interstitial lung diseases (SR-ILDs) by series of case report and literature review.Method Cases with respiratory bronchiolitis-interstitial l
MicroRNA-155 (miR-155) overexpression is often found in malignancies including lung cancer.The objective of this study is to verify the hypothesis, based on the results of bioinformatics analysis, tha
Objective NDM-1 (New Delhi metallo-β-Iactamase), a recently identified metallo-β-Iactamase (MBL), is reported to be detected in K/ebsiella spp.and E.coli among Enterobacteriaceae worldwide.Here, we ea
In a world that has become a global village, not much is seen on how this internet age has improved doctor-patient interactions and patient follow-up.This study tries to offer a more efficient way on
In the present study, we explored the effects of demethylation on lung function, lung cell apoptosis, lung mitochondrial cytochrome c oxidase (COX) activity, and mitochondrial transcription factor A (
目的:分析肌纤维发育不良(FMD)的临床、影像学特点及与脑血管病的关系,探索不同发病方式的治疗方法.方法:对1例脑出血的病人的MR、CTA等影像资料及临床特点进行分析,确诊为FMD,并提出诊断依据和治疗思路.结果:青年女性,因"反复头痛5年,加重1天"就诊,门诊查头颅CT提示"脑出血"入院,5年前曾因"脑出血"入院治疗,当时行"血肿清除术",术后遗有慢性头痛病史.