【摘 要】
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目的 Metastasis of cancer cells is a serious challenge to effective cancer therpy and prolonged survival time.It has beendiscovered that lncRNAs exert important functions on diverse biological processes
【机 构】
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Department of Respiratory Medicine,Jinling Hospital,Medical School of Nanjing University
【出 处】
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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议
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目的 Metastasis of cancer cells is a serious challenge to effective cancer therpy and prolonged survival time.It has beendiscovered that lncRNAs exert important functions on diverse biological processes,for instance proliferation,apoptosisandmetastasis.The lincRNA 00673 is a 2275-bp transcript on chromosome 17 with no protein-coding potential.Our Previouswork have found that up-regulated linc00673 in lung cancer tissues was positively correlated with tumor size,lymph nodemetastasis and TNM stage and promoted tumor cells proliferation in vitro and in vivo.Hence,we carry out this study toinvestigate its potential role in promoting lung cancer metastasis.
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