Nowadays nanosupramolecules have obtained more attention based on their potential applications in drug and delivery.Among the broad diversity of supramolecular species as building blocks,water-soluble macrocycles,cyclodextrins,a class of cyclic oligosaccharides with six to eight D-glucose units linked by a-l,4-glucose bonds,and sulfonatocalixarenes,a kind of phenol-formaldehyde cyclic oligomers,are widely studied owing to their desirable advantages including efficient binding to drug molecules,biocompatibility and low cytotoxicity.