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  5. Acute hypobaric hypoxia induces neuroinflammation and blood brain barrier leakage in mice

Acute hypobaric hypoxia induces neuroinflammation and blood brain barrier leakage in mice

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：dande
【摘 要】
：
Exposure to acute hypobaric hypoxia(AHH)during ascent to high altitudes(>3,500 m)pose a big challenge for those without adequate adaptation,which is the main cause of acute mountain sickness(AMS).Neur
【作 者】
：
Yanzhao Zhou Xin Huang Lijun Zhang Tong Zhao Ming Fan Lingling Zhu 
【机 构】
：
Department of Cognitive Sciences,Beijing Institute of Basic Medical Sciences,Beijing,P.R.China
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
hypoxia blood brain barrier neuroinflammation 
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　　Exposure to acute hypobaric hypoxia(AHH)during ascent to high altitudes(>3,500 m)pose a big challenge for those without adequate adaptation,which is the main cause of acute mountain sickness(AMS).Neuroinflammation has been reported to disrupt the blood brain barrier(BBB)and induce brain edema.The relationship between neuroinflammation and AHH is seldom investigated.
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