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研究背景：结直肠癌是严重威胁人类健康的重大疾病，转移是导致结直肠癌预后不良的关键因素。我们前期研究发现：负性共刺激分子B7-H3在结直肠癌中异常高表达，随着癌变过程的进展其表达水平也逐步上调，且与结直肠癌患者肿瘤转移的发生密切相关，但确切的机制尚待研究。
负性共刺激分子B7-H3与c-Met结合调控EMT促进结直肠癌的转移及机制
【摘 要】
：
研究背景：结直肠癌是严重威胁人类健康的重大疾病，转移是导致结直肠癌预后不良的关键因素。我们前期研究发现：负性共刺激分子B7-H3在结直肠癌中异常高表达，随着癌变过程的进
【机 构】
：
苏州大学附属儿童医院
【出 处】
：
第十四届全国肿瘤生物治疗大会
【发表日期】
：
2015年期
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