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5. ROS-responsive mitochondria-targeting blended nanoparticles for chemo-and photodynamic synergistic t

ROS-responsive mitochondria-targeting blended nanoparticles for chemo-and photodynamic synergistic t

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：xinshili100

【摘 要】

：

Mitochondria in cancer cells maintain a more negative membrane potential than normal cells[1].And mitochondria are the primary source of cellular reactive oxygen species (ROS),which are necessary for

【作 者】

：

Caixia Yue Yuming Yang Chunlei Zhang Gabriel Alfranca Daxiang Cui 

【机 构】

：

Institute of Nano Biomedicine and Engineering,Department of Instrument Science & Engineering,School

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

mitochondria-targeting nanoparticles ROS-responsive zinc phthalocyanine 

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　　Mitochondria in cancer cells maintain a more negative membrane potential than normal cells[1].And mitochondria are the primary source of cellular reactive oxygen species (ROS),which are necessary for photodynamic therapy (PDT).Thus,the strategy of targeting mitochondria can maximize the efficiency of PDT against cancer.

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