Objective It is generally accepted that epigenetics play a role in the regulation of infammatory genes in COPD.The present study aimed at understanding the regulation of histone methylation and DNA me
Object Investigate the relationships between hsa-mir-155 expression and lymph node metastasis in NSCLC tissues.We also explored the impact of expression of these miRNAs on invasive and migratory capab
Objective To analyze the value of 99mcTC-MIBI dynamic imaging in calculating the chemo sensitivity in NSCLC.Methods Retrospective analysis of 99mcTC-MIBI dynamic imaging of tumor tissue in 30 patients
Background Acute exacerbation of chronic obstructive pulmonary disease (COPD) (AECOPD) is an acute event characterized by worsening of the patients respiratory symptoms.It is often precipitated and ac
Introduction The coexistence of emphysema and pulmonary fibrosis is known as combined pulmonary fibrosis and emphysema (CPFE).The aim of this study was to compare diaphragmatic motion measured by M-mo
目的 研究神经生长因子在支气管哮喘气道重塑中发挥的作用及其可能机制,为哮喘治疗寻求新的靶点.方法 30只SPF级健康雄性Wisdar大鼠,随机分为健康对照组、哮喘模型维和NGF抗体干预组.健康对照组采用生理盐水致敏和激发,哮喘组采用鸡卵白蛋白(OVA)致敏和激发,干预组造模同哮喘组,但于第6次雾化激发起,激发前3h,先经鼻滴入兔抗大鼠NGFβ抗体.造模完成后采用HE染色观察大鼠气道壁组织学改变,M
Backgroud A systematic review was undertaken to evaluate the clinical effectiveness of roflumilast, a selective phosphodiesterase 4 inhibitor, on pulmonary function, exacerbation rate, quality of life
Object The structural changes and endocrine dysfunction of adrenal medullary chromaffin cells (AMCCs) are associated with the pathogenesis of asthma.Regular aerobic exercise can improve lung function
Aim RNA binding motif 5 (RBM5)is a tumor suppressor gene that modulates apoptosis through the regulation of alternative splicing of apoptosis-related genes.Our previous studies suggested that the RBM5
Background Statins showed beneficial effects on various types of animal models of pulmonary arterial hypertension (PAH), however, the clinical evidence of the treatment effects of statins on PAH patie