【摘 要】
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Objective To evaluate the possible influence of GHR t/d3polymorphism and four single nucleotide polymorphisms (SNP)in the IGFBP-3 gene on the growth response in Chinese idiopathic GH deficiency (GHD)
【机 构】
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Department of Endocrinology,PUMC Hospital,CAMS and PUMC,100730 Beijing,China
【出 处】
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中华医学会第十二次全国内分泌学学术会议
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Objective To evaluate the possible influence of GHR t/d3polymorphism and four single nucleotide polymorphisms (SNP)in the IGFBP-3 gene on the growth response in Chinese idiopathic GH deficiency (GHD) patients treated with rhGH over 3and 12 months.Participants and Methods 85 GHD patients and 100healthy subjects were recruited.Five polymorphisms mentioned above were determined for healthy subjects and patients.Clinical data for GHD patients included general information, medical history, diagnosis, therapy protocol, follow-up and other relatedinformation.
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