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5. GDC-0152 induces apoptosis through downregulation of XIAP in human leukemia cells and ihibition of P

GDC-0152 induces apoptosis through downregulation of XIAP in human leukemia cells and ihibition of P

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：lulaiyue

【摘 要】

：

Object The X-linked inhibitor of apoptosis(XIAP) is closely related to leukemia apoptosis.The present study was undertaken to determine the molecular mechanisms by which GDC-0152,an XIAP inhibitor,ind

【作 者】

：

Rong Hu Kun Yao Zhuogang Liu Miao Miao Jia Li Huinan Jiang Mengqi Li 

【机 构】

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Department of Hematology,Shengjing Hospital,China Medical University

【出 处】

：

The 35th World Congress of the International Society of Hema

【发表日期】

：

2014年5期

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Object The X-linked inhibitor of apoptosis(XIAP) is closely related to leukemia apoptosis.The present study was undertaken to determine the molecular mechanisms by which GDC-0152,an XIAP inhibitor,induces apoptosis in human leukemia cells(K562 cells).

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