Isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate rec

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：jxgalcj

【摘要】

：

【作者】

：

Juntang Li Yali Zhao Ting Wang Ningning Liu Qinqin Liu Xiaoshan Zhu Chunfang Gao Lintao Jia Angang Yang

【机构】

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Centre of Inflammation and Cancer Research,150th Central Hospital of PLA

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

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2015年10期

【关键词】

：

Isoflurane zymosan TLR2 NMDAR neutrophil

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　　Introduction: Neutrophil release of NO/ONOO- induces endothelial cell barrier dysfunction in inflammatory acute lung injury (ALI).Previous studies using zymosan-triggered inflammation and ALI model revealed that zymosan promotes inducible NO synthase (Inos) expression in neutrophils, and that isoflurane inhibits zymosan-induced oxidative stress and Inos biosynthesis.

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Isoflurane relieves zymosan-induced neutrophil inflammatory response by targeting NMDA glutamate rec

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