Protective effect of baicalein against myocardial ischemia-reperfusion injury in rats

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户:bear_flysky
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: To investigate protective effect of baicalein on myocardial ischemia-repeffusion injury in rats, Methods: The myocardial ischemia-reperfusion injury model was established in rats by ligating left anterior descending coronary artery.The contents of Na+-K+-ATPase, Ca2+-ATPase, lactic acid (LD), lactate dehydrogenase (LDH), and creatine kinase (CK) in myocardium were determined by chromatometry.
其他文献
Aim: Alzheimers disease (AD) is a multifactorial complex disease.The failure of recent development of AD therapeutic agents in clinical trials is partly due to their single-target effect.The purpose o
Aim: It was generally believed that excessive potassium efflux was one of the primary causes of neuronal injury after cerebral ischemia, so inhibition of the excessive potassium channels might play a
Aim: Chronic stress is implicated in many types of neurodegenerative diseases such as Alzheimers disease (AD).The present study investigated the effects of chronic restraint stress (CRS) on learning a
Aim: The deregulation of cyclin-dependent kinase 5 (Cdk5) by p25 and neuroinflammation has been linked to the pathogenesis in a number of neurodegenerative diseases such as Alzheimers disease (AD), AL
Aim: Previous studies showed that analgesic-antitumor peptide (AGAP) has analgesic activities tested.In this study, the effects of AGAP on ion channels including VGSC, VGCC and VGPC were investigated
Aim: It is established that glioma, the most common form of primary brain tumor, possess the characteristic of high incidence rate and difficult therapy.Recent studies indicated that Tamoxifen (TAM) c
Aim: Recently, research of the contribution of activated microglia in Alzheimers disease (AD) has become a new research hotspot.To further explore the role of reactive microglia in AD, we compare the
Considerable evidence exists that use of non-selective (eg, diclofenac) and cyclooxygenase (COX)-2 selective (eg, celecoxib) NSAIDs is associated with increased cardiovascular (CV) risk.Although the m
Aim: A tetrahydroisoquinoline-based hydroxamic acid derivative (ZYJ-34c) as histone deacetylase inhibitor, inhibited the growth of human breast carcinoma (MDA-MB-231) xenograft, a mouse hepatoma-22 (H
Aim: It was reported that phosphoprotein is involved in the regulation of ANP release.In this study, the effect of potassium bisperoxo(1,10-phenanthroline) oxovanadate [bpv(phen)], a protein tyrosine