Artemisinin was an effective antimalarial drug isolated from the herbalmedicine Artemisia aunna L[1-4].How to directly separate Artemisinin from natural crude material is an interesting subject[].Molecular imprinting technique provides a new choice for separation and purification of artemisinin.In addition,MIPs for artemisinin can replace silica gel which was used in the conventional purification process to improve the purity of extracted artemisinin.But few researches have focused their attention on the preparation of MIPs for artemisinin.In this work,the silica gel were used as supported materials,onto the surfaces of which vinyltriethoxysilane (VTES) was grafted.The preparation of MlPs for artemisinin was performed on the surfaces of the modified silica gel using artemisinin as the template,acrylamide (AM) and methacrylic acid (MAA) as the functional monomers,ethylene glycol dimethacrylate (EGDMA) as the cross-linker and 2,2′-azo-bis-isobutyronitrile (AIBN) as the initiator.Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR) were employed to characterize the prepared MIPs.The adsorption kinetic curve,adsorption isotherm and selective adsorption were measured by static method.The adsorption kinetics reached the equilibrium about 10h with the fast adsorption in the first 2-3h.The equilibrium adsorption quantity of MIPs for artemisinin was 32.44mg/g.The selectivity coefficient of MIPs and the relative selectivity coefficient was 2.29 and 2.03,respectively.The results showed that the MIPs possessed good specific adsorption capacity and selectivity for artemisinin.