A rare variant rs12731181 in the miR-590-3p target site of prostaglandin F2 receptor gene (FP) confe

来源 :2013 Shanghai Symposium on Polyunsaturated Fatty Acids and M | 被引量 : 0次 | 上传用户:jimmycjriyue
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Prostaglandin (PG) F2 receptor (FP), expressed abundantly in kidney and resistant arteries, plays an important role in fluid/electrolyte homeostasis and regulation of blood pressure (BP).In this study, we identified miR-590-3p regulates FP gene expression by binding to its 3-untranslated region (3UTR),where a variant- rs12731181(AG) is located.
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