【摘 要】
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The discovery and characterization of novel groups of proteins (cofactors) that participate in the transcriptional activity of nuclear receptors (NRs) have
【机 构】
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DepartmentofDevelopmentalBiologyMedicalSchoolofTampereUniversityFinland
论文部分内容阅读
The discovery and characterization of novel groups of proteins (cofactors) that participate in the transcriptional activity of nuclear receptors (NRs) have marked a new wave in the research of NR functioning.NRs, usually in a ligand-dependent manner, induce transcription of specific genes that regulate biological processes such as cell growth, differentiation and homeostasis.In its own turn, nuclear receptor cofactors, appear to be also directly involved in control of the developmental course.
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