急性早幼粒细胞白血病治疗进展

来源 :第十二届全国中西医结合血液学学术会议暨第三届中西医结合血液学高峰论坛 | 被引量 : 0次 | 上传用户:wuxi_xizi
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内容APL的治疗历程最新进展存在问题急性早幼粒细胞白血病(APL)曾是一个死亡率极高的疾病APL的根治率提高APL临床研究历程2013年前---APL治疗模式欧美:ATRA+化疗(循证级别高)中国:ATRA+砷剂+化疗国际治疗APL三个思路·上海:靶向性药物:ATRA-ATO·欧洲:ATRA+化疗(逐步减少化疗)·北京:口服砷剂代替静脉砷剂.
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主要内容1 概述◆2 移植方案与临床疗效3 我们中心病例总结4 展望AA概述AA为免疫介导骨髓衰竭·由多种原因引起:化学、物理、生物、遗传或不明因素·以骨髓造血功能衰竭,全血细胞减少为特征·主要临床表现:贫血、出血和感染·部分可最终演变成MDS、PNH或AML等克隆性疾病原发性AA占70%-80%中国21省SAA/AA 0.14/0.6(10万).
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从临床治疗引出的问题这部电视剧是八十年代中国千家万户必看的一部最动人的爱情故事.山口百惠、三浦友和成为中国人民最喜欢的日本明星.但白血病这个名词也深深的印在人们的脑海里八十至九十代初,当化疗是白血病、部分实体瘤必须依赖的治疗手段时,人们可以看到这样一个残酷的事实,就是肿瘤细胞对化疗药物越来越不敏感,最终导致临床疗效下降.
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