Methodology Development Inspired and Driven by Carbohydrate Chemistry

来源 :中国化学会第三届全国糖化学会议 | 被引量 : 0次 | 上传用户:qq602602
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Carbohydrate-containing molecules are ubiquitous in nature and essential to sustaining lives. The structural complexity of carbohydrates renders their synthesis and modification formidable tasks in synthesis, and significantly hampers the investigation and exploration of their biological roles.
其他文献
  硫糖是一类特殊的化合物,由于硫原子比氧原子具有更强的亲核性,更容易发生亲核取代反应,故含硫糖苷键的糖类似物或寡糖往往合成较容易,且糖苷键中的氧被硫取代后具有更好的柔
会议
  The 1,5-diazabicyclo[4.3.0]non-5-ene (DBN)-catalyzed regioselective acylation of carbohydrates and diols in ethyl acetate has been developed.
  3-氨基脱氧糖是一系列生物活性天然产物和药物的重要结构组成部分。尽管这类稀有糖在自然界中总体含量很低,但是种类非常丰富。整体而言,这些氨基糖可以分为两类:3,5-cis-3-
会议
  Peptidoglycan is the core component of every bacterial cell wall, which makes it anattractive target for the development of new bacterial targeting agents.
  利用金属-碳键构筑超分子功能体系是有机金属化学发展较快的领域之一[1]。近年来我们通过引入有机金属构筑基元,制备了系列具有不同空间结构和形状的有机金属功能体系,发现
  The Human Glycome is one of the large frontiers in science, and the Human Glycome Project (HGP) aimed to address this great challenge has formally be launch
会议
  糖链的体内酶促合成途径是一个非模板直接驱动的过程。由于酶的底物专一性限制,需要多个同工酶来完成不同糖链中相同糖苷键的构建,因而其产物呈现为微观不均一的混合物。此
会议
  C-aryl glycosides are widely found in nature and play important roles in drug design. Despite the significant progress made over the past few decades, effic
会议
  天然产物树脂糖苷Murucoidin Ⅴ是从旋花科牵牛属植物中分离出的一种大环内酯类化合物。研究发现,Murucoidin Ⅴ在对耐长春碱的人类乳腺癌细胞的细胞实验中能够255倍的增
会议
  According to recent database of Integrity, there are 461 carbohydrate based new drug on the clinical trial, including carbohydrate, glycosides, nucleosides,
会议