• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Tongxinluo dose-dependently decreases apoptosis of mesenchymal stem cells under hypoxia and serum de

Tongxinluo dose-dependently decreases apoptosis of mesenchymal stem cells under hypoxia and serum de

来源 :2013中国心脏大会(CHC) | 被引量 : 0次 | 上传用户：laohe200304
【摘 要】
：
Background and Objective Mesenchymal stem cells (MSCs) are one of the optimal candidates for myocardial infarction.However, the survival ratio of implanted cells in the infarcted heart is low.Tongxinl
【作 者】
：
Na Li Hehe Cui Qian Zhang Chen Jin Haiyan Qian Hao Zhang Yuejin Yang 
【机 构】
：
State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,National Canter for Cardiovascular Dis
【出 处】
：
2013中国心脏大会(CHC)
【发表日期】
：
2013年2期
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background and Objective Mesenchymal stem cells (MSCs) are one of the optimal candidates for myocardial infarction.However, the survival ratio of implanted cells in the infarcted heart is low.Tongxinluo (TXL) is a traditional Chinese herbal medicine with multiple cardiovascular protective effects and has been widely used in China to treat patients with coronary heart disease.MEK/ERK pathway plays an important role in mediating cell survival.Therefore, we hypothesized that TXL could promote MSCs survival under hypoxia and serum deprivation (H/SD) via MEK/ERK pathway.
其他文献
The effect of sildenafil on the pathology progress and mechanism research on pulmonary arterial hype
Objective To investigate the effects of sildenafil on the remodeling of pulmonary arterial and TNF-alpha expression in model induced by monocrotaline in pneumonectomized rats.
会议
A study of the effection on collagen and TGF-β1, AT1, CYP11 B2 of dilated cardiomyopathy by transpla
Objective To investigate transplantation of MSCs in treatment of DCM on the feasibility of TGF-β1, AT1, CYP11B2 and myocardial collagen expression.Method 1.Rate were injected ADR to build DCM model.
会议
Tirofiban improves renal outcome in a rat model of ischemia/reperfusion injury by modulating nO synt
Aim Renal ischemia/reperfusion (I/R) injury is a co mmon clinical disease.We have known that NO-signal transduction has an important effect on renal I/R injury.
会议
PHD2 silencing enhances the survival and paracrine function of transplanted adipose derived stem cel
Rationale Transplantation of stem cells into damaged hearts has had modest success as a treatment for ischemic heart disease.One of the limitations is the poor stem cell survival in the diseased micro
会议
Experiment of cellular repressor of E1Astimulated genes (CREG) delivery via nanoporous Stent in a po
Background In this study we investigate the in vitro pharmacokinetic of nanoporous CREG eluting-stent (CREGES) and evaluate the efficacy and safety of nanoporous CREGES in inhibiting neointima prolife
会议
Rosuvastatin prevents contrast-induced nephropathy in diabetic nephropathy rats
Background The aim of the present study was to assess the effects of rosuvastatin on contrast-induced nephropathy (CIN) in diabetic nephropathy rats.Methods Male SD rats,using a single intraperitoneal
会议
LincRNA-p21 feedback enhances P53 activity via interaction with MDM2 function in vascular smooth mus
Objective To investigate the relationship and molecular mechanism of lincRNA-p21 in the development of atherosclerosis (AS).Methods Firstly,we detected the expression of lincRNA-p21 expression in th a
会议
The relative contribution of paracine effect vs direct differentiation on adipose-derived stem cell
Background Recent studies have demonstrated that transplantation of adipose-derived stem cell (ADSC) can improve cardiac function in animal models of myocardial infarction (MI).
会议
CFD analysis & PIV experimental Study on the flow in inlet & outlet cannulas of FW-2 ventricular ass
Objective To analyze and test the hydraulic characteristics of the blood flow in the inlet and outlet cannulas of FW-2 ventricular assist pump with the Methods of computational fluid mechanics (CFD) a
会议
Influence of genetic polymorphisms of uptake (OATP1B1) and efflux (BCRP/MRP2) transporters on the ph
Objective The aim of the present study was to investigate the contribution of genetic polymorphisms of uptake (OATP 1B1) and efflux (BCRP/MRP2) transporters on the pharmacokinetics of rosuvastatin in
会议