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5. Second-order calibration method applied to process three-way excitation-emission-kinetic fluorescenc

Second-order calibration method applied to process three-way excitation-emission-kinetic fluorescenc

来源 :第十五届国际电分析化学国际会议(The Fifteenth International Symposium on Ele | 被引量 : 0次 | 上传用户：yumimiteresa

【摘 要】

：

Methods to monitor the metabolic transformations of pharmaceuticals in a real-time and rapid fashion are required to develop safe and effective drugs.Lactone hy

【作 者】

：

Xiao-Li YIN Hai-Long WU Hui-Wen GU Yong HU Hui XIA L.WANG Ru-Qin YU 

【机 构】

：

StateKeyLaboratoryofChemo/BiosensingandChemometrics,CollegeofChemistryandChemicalEngineering,HunanUn

【出 处】

：

第十五届国际电分析化学国际会议(The Fifteenth International Symposium on Ele

【发表日期】

：

2015年8期

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论文部分内容阅读

Methods to monitor the metabolic transformations of pharmaceuticals in a real-time and rapid fashion are required to develop safe and effective drugs.Lactone hydrolysis is one of the most important metabolic transformations; it occurs readily in pharmaceuticals containing lactones by both enzymatic and non-enzymatic processes.

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